COLOR NUTRITION

This is an interview by Christine Gable with Walter Last for an article in the May 07 issue of the N.Y. magazine Better Nutriton.

1. Blueberries and blackberries boast fiber and anticancer qualities, thanks to the pigment anthocyanin. Why is anthocyanin beneficial? Are there any other compounds that make dark colored fruits and veggies grand?

Anthocyanins and related compounds belong to the group of flavonoids and are polyphenols with three carbon rings that are responsible for the red, purple, and blue colors of fruits, vegetables, and flowers. Various studies have shown that mortality from cardiovascular disease is inversely correlated with the intake of flavonoids in the diet, they also have anti-microbial activities and help with cancers, strokes, vascular problems and all kinds of inflammatory conditions. They are helpful with diabetic retinopathy and macular degeneration, especially beneficial are the purple pigments in Bilberries for improving night vision or visual acuity and circulatory disorders.  

The main benefits of anthocyanins are probably due to their strong antioxidant and free-radical quenching activity. Most foods contain a variety of anthocyanins and related compounds. There exist thousands of variations of the basic molecular configuration, and the specific health effect of most of these is still unknown. One such ingredient that has in recent years risen to prominence is resveratrol from the skin of grapes.  

It is attributed with inhibiting fungal infections, inflammations, cancers, metastases, heart disease, Alzheimer's disease and other age-related brain disorders, raising good HDL cholesterol, lowering PSA levels in males, increasing immunity, controlling blood pressure, preventing blood clots and strokes, and extending the lifespan by switching on a “longevity gene.” While it is mainly ingested as an ingredient of red wine, supplements are now available of whole grape skins which seem to be more beneficial than more purified resveratrol. Also grape seed extract has similar impressive health benefits.

2. Green veggies are well known as being an important part of a healthy diet. What exactly is it about green vegetables that makes them so super?

The obvious feature of green veggies is the green color due to chlorophyll. Chlorophyll is a protein with the same structure as hemoglobin, and therefore with a desirable amino acid composition.  Veggies have a very favorable protein to carbohydrate ratio. While low in fats they are relatively high in alpha linolenic acid, a desirable omega-3-fatty acid. In regard to vitamins they are especially high in vitamin K and folate, or folic acid, which are generally deficient with most individuals. They are low in pro-inflammatory phosphorus but high in anti-inflammatory calcium and magnesium.  

Spinach is one of the best sources of magnesium, listed as 88 mg/100 g, which can be more difficult to obtain from food than calcium. Green veggies are also high in desirable fiber to feed the bowel bacteria and prevent constipation. The overall composition is such that it is a highly desirable food for cancer and all inflammatory conditions. However, this assumes that vegetables are steamed or that the cooking water is ingested because it contains most of the beneficial vitamins and minerals. 

Even more beneficial are green leaves, or wheat or barley grass as freshly pressed or frozen juices or as commercial powders, usually organic and still high in enzymes. For remaining young longer enzymes generally are even more important than vitamins and minerals. This is also the advantage of raw green salads. Generally the best base for an anti-inflammatory and anti-cancer diet is a combination of chlorophyll-rich foods such as spirulina, chlorella, barley or wheat grass powders, fresh raw, juiced and cooked green vegetables, and other colored foods.     

3. In your book you write about the benefits of purple foods. Can you tell me more about the purple pigment betacyanin--why/how does it turn purple foods into powerhouses?

There are four main classes of plant pigment: chlorophylls, carotenoids, flavonoids and betalains. Betacyanin is a betalain and the purple-crimson pigment in red beet or beetroot and prickly pear. Like most of the bioflavonoids it is water soluble while chlorophylls and carotenoids are insoluble in water.

Red beet is rich in important minerals and micronutrients (especially folate/folic acid) but its many health benefits are mainly due to its two ingredients betacyanin and betaine. Traditionally it was regarded as being beneficial for the blood, heart and digestive system and was used as a laxative, for bad breath, coughs, headaches, and more recently also as an immune stimulant and anti-cancer agent. In Roman times as well as in modern India and parts of England red beet and its juice were considered to be an aphrodisiac.

Red beets have been used for centuries in the treatment of cancers, and for this betacyanin is probably the active ingredient, although the alkaloid allantoine in beets has also an anti-tumour effect. In modern times it came to prominence with reports of promising results by the Hungarian physician Alexander Ferenczi in the 1950s.

In the 1960s several cancer researchers, especially the German P.G. Seeger, demonstrated that the metabolism of cancer cells could be normalized with the pigments in beet juice. However, cancer cells with high-grade malignancy as after chemotherapy or radiotherapy could no longer be normalized, although beet juice was still helpful.

Red beets were also an important part of the recent South African fight against HIV and AIDS, although this has now been de-railed by the proponents of drug treatments. 

Betaine in red beet is a mood modifier; it relaxes the mind and is useful for depression. Chemically betaine is trimethylglycine (TMG) and related to choline. With this it is needed for producing neurotransmitters, especially serotonin, and as a methyl donor it is important for the liver and the fat metabolism. It also lowers levels of homocysteine and with this reduces the risk of heart disease and strokes.

Some people pass red urine (beeturia) and red stool, even after eating only a modest amount of beetroot. This may be overcome with magnesium supplements; also iron deficiency is often present with beeturia. 

4. Do all foods that are red, blue or purple contain bioflavonoids? What should people know about bioflavonoids?

Basically all foods that produce a red, blue or purple juice when pressed with skin contain bioflavonoids or betalains. If just the skin is colored, such as with apples, eggplant and some sweet potatoes there may be colorless polymers present inside that can still have a high antioxidant value. However, by far the highest flavonoid content is usually in the skin. Yellow and orange foods are commonly colored by carotenes with a different chemical structure.  

Flavonoids is the name for thousands of polyphenolic plant chemicals with a three-ringed structure. Those that are biologically most active are also called bioflavonoids. Nutritionally important sub-groups of flavonoids are the anthocyanins, the citrus bioflavonoids and the tea polyphenols.  

Citrus bioflavonoids have quercetin as the basic chemical structure; common members include rutin, quercitrin, hesperidin, and naringin. These remain generally in the pulp after pressing out the juice. To extract the bioflavonoids blend the pulp or inner skin with some water and strain.

 When many individual anthocyanin molecules are linked together they are also called proanthocyanidins and oligo-proanthocyanins or OPC's. One such compound is commercially extracted from pine bark as pygnogenol while grape seed extract has similar qualities.  

The flavonoids in tea are based on catechin, the main active ingredient is epicatechin. It improves blood flow and thus seems good for the heart but also helpful with cancer. Cocoa as in dark chocolate contains high amounts of epicatechin and has nearly twice the antioxidant value of red wine and up to three times that of green tea. The catechins in black tea are more oxidized and less active than in green tea.  

However, adding cows' milk to tea eliminates its beneficial effect on the heart as caseins in milk render the catechins inactive. While the catechins in tea are beneficial, the tea itself is now so very high in fluoride that regular consumption may be a health danger, especially in fluoridated areas. It may be better to use cocoa instead with its much higher antioxidant power, provided you can do so without adding cows' milk, goats' milk should be acceptable.  

Another group of flavonoids that I would give a miss are the soy isoflavones (e.g. Genistein and Daidzein). There is a high probability that they are produced from GM soy. Also because of the high concentrations of anti-nutrients in soy foods these are only healthy if they are traditionally fermented (this may not apply to lecithin because it does not contain soy proteins). There are also concerns about the effects of soy phytoestrogens on our natural hormone balance.  

Bioflavonoids are powerful antioxidants, and their acknowledged health benefits include anti-microbial, anti-inflammatory, anti-cancer, antihistamine and anti-allergy effects. They work synergistically with vitamin C, decrease capillary permeability and fragility, and protect collagen, blood vessels and the heart.  

In conclusion I recommend reducing "empty" calories from sugar and white flour to the barest minimum and use instead a wide range of colored fruit, vegetables and spices. 

5. Is it correct that spinach, lettuce, broccoli and peas contain lutein and zeaxanthin? Are they carotenoids that help protect the eyes from macular degeneration?

There are two groups of carotenoids, carotenes, such as beta carotene, and xanthophylls with lutein and zeaxanthin. Both groups form yellow and orange plant pigments.

The chemical structures of both are nearly identical but they seem to perform different functions in the macula of the eye, as the concentration of zeaxanthin is highest in the center, and lutein in the periphery of the macula. They are also found in the lens and so may protect against cataracts as well as age-related macular degeneration (AMD) and some forms of cancer. Their main function seems to be as antioxidants, protecting the eye from ultraviolet light and free radicals. They may improve vision in retinitis pigmentosa, are helpful in glaucoma and stimulate immune functions.

Both tend to occur in the same foods and are often reported together. Lutein is usually present in much higher amounts than zeaxanthin. Kale contains the highest amount of lutein in a vegetable with 21.9 mg/100 g but contains only 0.173 mg/100 g of zeaxanthin. Corn with .78 mg/100 g of lutein has the highest amount of zeaxanthin at 0.528 mg/100 g. Spinach has a combined value of about 12 mg/100 g. Next come turnip leaves and collards, and other foods have much less. The amount of lutein in chicken egg yolk is approximately 290 micrograms per yolk, and of zeaxanthin 210 micrograms per yolk, or combined 3 mg per 100 g. Sometimes also higher or lower values can be found in food tables.

A recommended food supplement with high values of lutein and zeaxanthin is spirulina. Two teaspoons or 10 g provide 6 to 8 mg with about 3 mg of zeaxanthin. Lutein is commercially extracted from marigold petals as a food coloring, especially to add to chicken feed for coloring the yolk. The lutein content of these petals is about 1%.

Lutin and zeaxanthin, like all carotenoids, are fat soluble. Therefore to absorb them they need to be ingested with fat or oil, preferably in addition to some lecithin for better absorption. Unfortunately, there is now widespread mineral and fat malabsorption due to the twins of gluten sensitivity and antibiotic use causing dysbiosis, and this makes it very difficult for affected individuals to absorb these nutrients even from a good diet and even less from tablets. The solution is generally intestinal sanitation with garlic and probiotics to improve absorption.

 

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